{"id":15,"date":"2026-09-22T13:58:15","date_gmt":"2026-09-22T13:58:15","guid":{"rendered":"https:\/\/www.digitalizedera.com\/bio-mimetic\/?page_id=15"},"modified":"2026-10-07T15:16:28","modified_gmt":"2026-10-07T15:16:28","slug":"home","status":"publish","type":"page","link":"https:\/\/www.digitalizedera.com\/bio-mimetic\/","title":{"rendered":"Home"},"content":{"rendered":"\t\t
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STEVENAGE, UK SINCE 2015\n<\/h4>\t\t\t\t<\/div>\n\t\t\t\t
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The consultancy for<\/span> successful<\/span> drug discovery<\/span> <\/h2>\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t
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Biomimetic HPLC measurements and ADMET predictions for early drug discovery<\/strong><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t
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From a very small amount of compound, we perform six chromatographic measurements and use the resulting experimental data in 22 validated models to predict key ADMET and in vivo distribution properties, including plasma protein binding, volume of distribution, blood\u2013brain distribution and tissue binding.

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The approach helps drug-discovery teams select compounds with more favourable properties earlier, reducing the risk of costly late-stage failure. Measurements can be performed rapidly at a fraction of the cost of many animal studies, while reducing the need for animal experiments.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t

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How the method works<\/a><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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\r\n Assay Panel\r\n <\/h2>\r\n <\/div>\r\n\r\n \r\n
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\r\n IAM\r\n <\/div>\r\n
\r\n Immobilised artificial membrane affinity\r\n <\/div>\r\n <\/div>\r\n\r\n
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\r\n HSA\r\n <\/div>\r\n
\r\n Human serum albumin binding\r\n <\/div>\r\n <\/div>\r\n\r\n
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\r\n AGP\r\n <\/div>\r\n
\r\n \u03b11-acid glycoprotein binding\r\n <\/div>\r\n <\/div>\r\n\r\n
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\r\n CHI logD\r\n <\/div>\r\n
\r\n Lipophilicity, pH 2 \/ 7.4 \/ 10.5\r\n <\/div>\r\n <\/div>\r\n \r\n\r\n <\/div>\r\n\r\n \r\n
\r\n Comprehensive Biomimetic profiling from\r\n \r\n \u00a3420 per compound\r\n <\/span>\r\n <\/div>\r\n\r\n <\/div>\r\n\r\n <\/div>\r\n\r\n\r\n