{"id":55,"date":"2026-09-22T14:10:40","date_gmt":"2026-09-22T14:10:40","guid":{"rendered":"https:\/\/www.digitalizedera.com\/bio-mimetic\/?page_id=55"},"modified":"2026-10-06T18:12:33","modified_gmt":"2026-10-06T18:12:33","slug":"about","status":"publish","type":"page","link":"https:\/\/www.digitalizedera.com\/bio-mimetic\/about\/","title":{"rendered":"About"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"55\" class=\"elementor elementor-55\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a25517e e-con-full e-flex e-con e-parent\" data-id=\"a25517e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-209ff77 elementor-widget elementor-widget-page-title\" data-id=\"209ff77\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"page-title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\n\t\t<div class=\"hfe-page-title hfe-page-title-wrapper elementor-widget-heading\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.digitalizedera.com\/bio-mimetic\">\n\t\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\n\t\t\t\t\t\t\t\t\n\t\t\t\tAbout  \n\t\t\t<\/h2 > \n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8b767cb elementor-widget elementor-widget-hfe-breadcrumbs-widget\" data-id=\"8b767cb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"hfe-breadcrumbs-widget.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<nav aria-label=\"Breadcrumb\"><ul class=\"hfe-breadcrumbs hfe-breadcrumbs-show-home\"><li class=\"hfe-breadcrumbs-item hfe-breadcrumbs-first\"><span class=\"hfe-breadcrumbs-home-icon\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-home\" viewBox=\"0 0 576 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M280.37 148.26L96 300.11V464a16 16 0 0 0 16 16l112.06-.29a16 16 0 0 0 15.92-16V368a16 16 0 0 1 16-16h64a16 16 0 0 1 16 16v95.64a16 16 0 0 0 16 16.05L464 480a16 16 0 0 0 16-16V300L295.67 148.26a12.19 12.19 0 0 0-15.3 0zM571.6 251.47L488 182.56V44.05a12 12 0 0 0-12-12h-56a12 12 0 0 0-12 12v72.61L318.47 43a48 48 0 0 0-61 0L4.34 251.47a12 12 0 0 0-1.6 16.9l25.5 31A12 12 0 0 0 45.15 301l235.22-193.74a12.19 12.19 0 0 1 15.3 0L530.9 301a12 12 0 0 0 16.9-1.6l25.5-31a12 12 0 0 0-1.7-16.93z\"><\/path><\/svg><\/span><a href=\"https:\/\/www.digitalizedera.com\/bio-mimetic\"><span class=\"hfe-breadcrumbs-text\">Home<\/span><\/a><\/li><\/ul><\/nav>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-33539b5 e-con-full e-flex e-con e-parent\" data-id=\"33539b5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-7f9bf0a e-con-full e-flex e-con e-child\" data-id=\"7f9bf0a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-a5878fa e-con-full e-flex e-con e-child\" data-id=\"a5878fa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5660a52 elementor-widget elementor-widget-heading\" data-id=\"5660a52\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Dr Klara Valko \u2013 Founder &amp; Scientific Director<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-045890d e-con-full e-flex e-con e-child\" data-id=\"045890d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-6d402c0 e-con-full e-flex e-con e-child\" data-id=\"6d402c0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-67d1852 elementor-widget elementor-widget-text-editor\" data-id=\"67d1852\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span data-olk-copy-source=\"MessageBody\">Dr Klara Valko is the founder and Scientific Director of Bio-Mimetic Chromatography Ltd and an internationally recognised pharmaceutical scientist specialising in physicochemical and biomimetic chromatography for drug discovery<\/span>.<\/p><p>Before establishing Bio-Mimetic Chromatography, she spent\u00a0<strong>22 years at GlaxoSmithKline and GlaxoWellcome in early drug discovery<\/strong>, developing and applying physicochemical and biomimetic methods to support compound optimisation.<\/p><p>During her pharmaceutical industry career, she supported\u00a0<strong>27 neuroscience drug-discovery programmes<\/strong>, together with multiple respiratory, oncology and topical drug-delivery programmes, providing experimental physicochemical data, structure\u2013property analysis and predictive models to guide compound design and selection.<\/p><p><span style=\"font-size: 1rem;\">Her scientific contributions include the development and application of high-throughput chromatographic methods for characterising<\/span><span style=\"font-style: inherit; font-weight: inherit;\">:<\/span><\/p><ul><li>Chromatographic Hydrophobicity Index (CHI) and lipophilicity<\/li><li>Human serum albumin (HSA) binding<\/li><li>Alpha-1-acid glycoprotein (AGP) binding<\/li><li>Immobilised Artificial Membrane (IAM) phospholipid binding<\/li><li>Environment-dependent hydrophobic surface exposure<\/li><li>Physicochemical and biomimetic properties relevant to drug absorption and distribution<\/li><\/ul><p><span style=\"font-size: 1rem;\">These experimental measurements have been incorporated into models for estimating key drug-discovery properties, including <b>oral absorption, permeability, volume of distribution, blood\u2013brain distribution, tissue binding and drug-efficiency indices<\/b><\/span><span style=\"font-style: inherit; font-weight: inherit;\">.<\/span><\/p><p>Dr Valko is the author of\u00a0<strong>more than 120 scientific publications<\/strong>\u00a0and has written and edited books on chromatography and its application to pharmaceutical research.<\/p><p>Her book,\u00a0<em>Physicochemical and Biomimetic Properties in Drug Discovery: Chromatographic Techniques for Lead Optimization<\/em>, describes the principles and practical application of chromatographic measurements for compound optimisation and prediction of in vivo drug behaviour.<\/p><p><span style=\"font-size: 1rem;\">She is an Honorary Professor at the UCL School of Pharmacy, where she contributes to teaching and research in physicochemical and ADME principles and the application of HPLC in drug discovery.<\/span><\/p><p><!--StartFragment--><span data-olk-copy-source=\"MessageBody\">During her 22-year pharmaceutical industry career, these high-throughput chromatographic methodologies were applied to approximately 500,000 compounds, supporting compound optimisation across multiple drug-discovery programmes.<\/span><\/p><p><!--EndFragment--><\/p><p><span style=\"font-size: 1rem;\">Today, the methodologies and models developed through this work form the scientific foundation of the Bio-Mimetic Chromatography platform. Since the company was established, Bio-Mimetic Chromatography Ltd has measured <b>more than 6,000 compounds for pharmaceutical and biotechnology clients across more than 20 companies<\/b>.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e3bdd04 e-con-full e-flex e-con e-parent\" data-id=\"e3bdd04\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;slideshow&quot;,&quot;background_slideshow_gallery&quot;:[{&quot;id&quot;:1833,&quot;url&quot;:&quot;https:\\\/\\\/www.digitalizedera.com\\\/bio-mimetic\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/bggg.png&quot;}],&quot;background_slideshow_loop&quot;:&quot;yes&quot;,&quot;background_slideshow_slide_duration&quot;:5000,&quot;background_slideshow_slide_transition&quot;:&quot;fade&quot;,&quot;background_slideshow_transition_duration&quot;:500}\">\n\t\t<div class=\"elementor-element elementor-element-ef34868 e-con-full e-flex e-con e-child\" data-id=\"ef34868\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-4ac1aa5 e-con-full e-flex e-con e-child\" data-id=\"4ac1aa5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bcee98a elementor-widget elementor-widget-heading\" data-id=\"bcee98a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Explore the Science<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f3b0f4a elementor-widget elementor-widget-eael-creative-button\" data-id=\"f3b0f4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-left\" href=\"https:\/\/scholar.google.com\/citations?user=nQo5KZkAAAAJ&#038;hl=en\" target=\"_blank\" data-text=\"Google Scholar Profile\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                                            <span class=\"eael-creative-button-icon-left\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-user\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224 256c70.7 0 128-57.3 128-128S294.7 0 224 0 96 57.3 96 128s57.3 128 128 128zm89.6 32h-16.7c-22.2 10.2-46.9 16-72.9 16s-50.6-5.8-72.9-16h-16.7C60.2 288 0 348.2 0 422.4V464c0 26.5 21.5 48 48 48h352c26.5 0 48-21.5 48-48v-41.6c0-74.2-60.2-134.4-134.4-134.4z\"><\/path><\/svg><\/span>                    \n                    <span class=\"cretive-button-text\">Google Scholar Profile<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e0d599b elementor-widget elementor-widget-eael-creative-button\" data-id=\"e0d599b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-left\" href=\"https:\/\/www.amazon.co.uk\/Physicochemical-Biomimetic-Properties-Drug-Discovery\/dp\/1118152123\" target=\"_blank\" data-text=\"Go to Books\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                                            <span class=\"eael-creative-button-icon-left\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-book-reader\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M352 96c0-53.02-42.98-96-96-96s-96 42.98-96 96 42.98 96 96 96 96-42.98 96-96zM233.59 241.1c-59.33-36.32-155.43-46.3-203.79-49.05C13.55 191.13 0 203.51 0 219.14v222.8c0 14.33 11.59 26.28 26.49 27.05 43.66 2.29 131.99 10.68 193.04 41.43 9.37 4.72 20.48-1.71 20.48-11.87V252.56c-.01-4.67-2.32-8.95-6.42-11.46zm248.61-49.05c-48.35 2.74-144.46 12.73-203.78 49.05-4.1 2.51-6.41 6.96-6.41 11.63v245.79c0 10.19 11.14 16.63 20.54 11.9 61.04-30.72 149.32-39.11 192.97-41.4 14.9-.78 26.49-12.73 26.49-27.06V219.14c-.01-15.63-13.56-28.01-29.81-27.09z\"><\/path><\/svg><\/span>                    \n                    <span class=\"cretive-button-text\">Books &amp; Publications<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>About Home Dr Klara Valko \u2013 Founder &amp; Scientific Director Dr Klara Valko is the founder and Scientific Director of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-55","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/pages\/55","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/comments?post=55"}],"version-history":[{"count":64,"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/pages\/55\/revisions"}],"predecessor-version":[{"id":2304,"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/pages\/55\/revisions\/2304"}],"wp:attachment":[{"href":"https:\/\/www.digitalizedera.com\/bio-mimetic\/wp-json\/wp\/v2\/media?parent=55"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}